GHRP-6 is a growth hormone releasing protein that has no opioid activity, creates a huge pulse, (dose dependent) in one’s own GH levels, and as an outcome, increased IGF-1 secreted by the liver. Suppresses somatostatin (the body’s own braking system for GH). GHRP-6 can create a huge and very intense increase in appetite, about 20 mins. after the
initial injection. This is caused by the GHRP-6 antagonizing the peptide Ghrelin, it mimics it, but actually fights against it causing the signal for gastric emptying and hunger. GHRP-6 may help reduce fat, by antagonizing Ghrelin. GHRP-6 creates an incredible anabolic effect and increased strength. Synergy when used with a GHRH, such as CJC-1295.
Ipamorelin is a growth hormone releasing protein, (GHRP), receptor-active GH secretagogue, it doesn=E2=80=99t significantly affect cortisol or prolactin, so it’s highly specific for GH release. It is very similar in action to GHRP-6 with no hunger as a side reaction. It has the capability of increasing bone mass. Ipamorelin acts with synergy
during GHRH pulsation. A large dose of Ipamorelin (>300mcg) will result in a maximum release of GH, very close to the entire volume stored in the pituitary, whereas, GHRP-6 has a limit of GH release.
Comparison of GHRP-6 and Ipamorelin:
- GHRP-6 is highly anabolic and a liver protectant
- Ipamorelin is highly capable of maximal GH release and almost no side effects
- both can increase recovery and maturation of satellite muscle cells
CJC-1295 w/o DAC is a Growth Hormone Releasing Hormone, GHRH. It affects both the number of secreting cells and the amount they are actually able to secrete. GHRH and GHRP are released in specific patterns that vary depending on what is involved, or has been occurring. Now CJC-1295 DAC has been proven to stimulate slow wave sleep, and this is the period of during sleep when most of the body is repairing itself, CJC-1295 works by repairing muscles and tissues.
The synergy between GHRP and GHRH is due to both the suppression of somatostatin and the increases in GH release per-somatotrope, while GHRH increases the number of somatotropes that release GH. CJC-1295 with DAC causes an extended bleed on the pituitary of GH that is not necessary in this formulation.
Muscle growth factor (MGF) or IGF-1Ec, proliferates (increasing in amount) myoblasts, which are stem cells that are used for creating muscle fibers. Muscles do not undergo mitosis like other cells, instead they must have myoblasts fuse to the area and be activated. MGF proliferates cells in their mononucleated states (muscle stem cells), which is an important mechanism since without these new stem cells there can be no new growth. The inability of this mechanism is seen in diseases like, muscular dystrophy and although MS patient’s bodies produce IGF-1, their muscles do not exhibit MGF expression, demonstrating the important role of MGF in recovering damaged muscle tissue.
Amino Acid profiles
Glycine is a nonessential amino acid contained in gelatin protein and is an important component of collagen. Although much of the early research revolved around glycines ability to increase strength in athletes, more recent studies have documented that oral glycine can indeed raise growth hormone levels in humans. In fact, researchers have hypothesized that the reason glycine has been found to increase muscle strength in many studies, (with females experiencing a 22% increase and men a 32% increase in cycle ergometry workloads after ingestion of 5 to 12 grams of glycine daily) may be the result of its growth-hormone-boosting capabilities.24